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essentially the most examined membrane receptor for MIF is CD74, often called HLA course II histocompatibility antigen gamma chain. in step with its part being a MHC class II chaperone, the highest CD74 expression is observed on the surface of antigen-presenting cells like dendritic cells, B cells, and macrophages [40]. on MIF engagement, CD74 recr

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have revealed that therapy with D-DT protected isolated hearts against damage and contractile dysfunction after ischemia–reperfusion. The protecting result of D-DT also necessary activation of adenosine monophosphate-activated protein kinase, which was also mediated through a CD74-dependent system [146]. DDTL here has about 70% sequence identity

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